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(Wiley) In an Epilepsia analysis of 2008-2010 Medicare claims data, one in four older Americans with new-onset epilepsy and more than one-third with prevalent epilepsy received a combination of antiepileptic drugs and non-epilepsy drugs that could interact to alter the effectiveness of the non-epilepsy drugs. Also, more than 1 in 5 patients received a drug combination that could alter the effect of the antiepileptic drugs and potentially cause toxicity.
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